Optical coherence tomography in desferrioxamine ocular toxicity: a place in screening and monitoring?

摘要

Desferrioxamine (DFO) is a chelating agent for the treatment of iron overload with well recognised ocular and ototoxicity. This case report illustrates an optic neuropathy in DFO ocular toxicity undetected on slitlamp biomicroscopy examination but illustrated by optical coherence tomography (OCT).A 74-year-old female myelofibrosis patient weighing 10.5 stones on 1.5 g of subcutaneous DFO presented with deteriorating vision associated with moderate neurosensory deafness. DFO toxicity was diagnosed and treatment ceased.