Prevention of sow uterine inflammation.

摘要

The objectives of this study were to observed the vaginal and uterine microflora in postpartum sows and to determine the efficacy of antibiotic preparations (2.5% Cobactan, Metricure, and ClamoxylReg. Metritis) in the prevention of postpartum inflammation of the uterus of sows. Smears from the cervix were taken from 56 sows and examined bacteriologically before parturition. Bacteriological examinations revealed that the smears were composed of 85.4% mixed microflora (Enterobacter, Streptococcus and Staphylococcus sp. at 42.9, 57.1 and 62.3%, respectively) and 14.3% pure (Staphylococcus sp.) cultures. Then, the animals were divided into 4 equal groups immediately after parturition and treated with the following: Group I, 2.5% Cobactan (4 ml/100 kg) i.m. once daily for 2 consecutive days; Group II, 2.5% Cobactan (4 ml/100 kg) i. m. once daily, for 2 consecutive days and additionally a single intrauterine dose of Metricure; Group III, a single intrauterine dose of ClamoxylReg. Metritis; Group IV, control. All manipulations were limited to the observation of uterine involution. Samples from the cervix of the uterus were taken 4-5 days after repeated treatment. Treatment efficacy was determined by artificial insemination index after weaning, number of piglets born alive and dead, mean weight of litter and piglets at weaning, and litter weight at weaning. After treatment, bacteriological examination of cervical samples showed that 50% of group I had pure cultures and mixed cultures in the other 50%. For group II, pure cultures were isolated in 42.8% of the pigs and mixed cultures in 14.3% of the samples. No microbial growth was observed in 42.9% of the samples. For group III, pure cultures were isolated in 37.1% of the samples, and mixed cultures in 21.4%. No growth was noted in 41.4% of the samples. For group IV, 14.3 and 85.7% pure and mixed cultures were isolated, respectively. After weaning, 1.5 semen doses for group I, 1.0 dose for groups II and III and 1.64 semen doses for group IV were used to determine the fertility of the sows. The number of piglets born alive and weight of piglets were approximately equal in all experimental groups and in control group, but mean weight of litter was higher in experimental groups, especially for groups II and III. It is concluded that intrauterine treatment with antimicrobial preparations ensures a sterile environment during puerperal period. Histological investigations of culled sows confirmed uterine inflammatory processes in the control group..