COMPOUND; PHARMACEUTICAL COMPOSITION; METHOD OF CONTRACEPTION, TREATMENT OR PREVENTION OF FIBROIDS, UTERINE LEYOMIOMAS, ENDOMETRIOSIS, DIFFICTIONAL BLEEDING, UTERINE FIBROIDS AND OVARIOUS POLYTICAL SYNDROME OR TO PROVIDE REPORTER THERAPY AND METHOD FOR TREATMENT OR PREVENTION OF HORMON DEPENDENT CARCINOMAS, FOOD INGESTATION STIMULATION OR STRUCTURE SYNCHRONIZATION

摘要

Compounds of the following structure are described: wherein R1, R2, R5, R6, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful for treating a variety of hormone-related conditions including contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake or synchronizing estrus.