Abstracts of Spineweek 2012 Meeting of the Spine Society of Europe. May 28-June 1, 2012. Amsterdam, The Netherlands.

摘要

Indeed, Platelet-rich plasma (PRP) can stimulate osteo-protegerin production which can lead to a decreased che-motaxis of osteoclasts. PRP can induce the production of. vascular endothelial growth factor (VEGF), leading to inhibition of osteoclast differentiation. Both mechanisms are well documented.Besides VEGF, platelet-derived growth factor (PDGF), and transforming growth factor beta (TGF-beta) are among the known growth factors to be important in bone healing. PRP can influence the concentration of these factors.