Re: Transperineal magnetic resonance image targeted prostate biopsy versus transperineal template prostate biopsy in the detection of clinically significant prostate cancer

摘要

Expert's summary: Multiparametric magnetic resonance imaging (MRI) can be used to guide prostate biopsy (PBx) to improve the diagnosis of cancer. The authors compared the efficacy of transperineal MRI targeted biopsy (MRI-TB) with transperineal template PBx (TPB). Both procedures were performed successively in each enrolled patient. In the sample of 182 men, the median prostate-specific antigen (PSA) level was 6.7 ng/ml, and transperineal MRI-TB was more efficient than TPB in detecting clinically insignificant prostate cancer (PCa; 9.3% vs 17.0%, respectively; p = 0.024). A higher proportion of cores were positive for cancer using MRI-TB (38% vs 14%). Despite fewer biopsies taken per patient with MRI-TB compared with TPB (5 vs 30), the cancer-detection rates were similar (57% vs 62%; p = 0.174). The authors concluded that these encouraging results should be confirmed by prospective, multicenter, comparative trials.