High-Resolution Magnetic Resonance Imaging of Prostatectomy Specimens: A Promising Tool for Virtual Histology

摘要

There is currently a wide range of opinion on the role of diagnostic imaging in prostate cancer (PCa). Approaches to the problem vary throughout the world [1 ]. Amid the debate there is a consensus that magnetic resonance imaging (MRI) is the most useful imaging modality, and since there are many physical mechanisms that produce image contrast via MRI, a large body of work has been published in this area over many years However, current MRI-based imaging still has suboptimal resolution relative to the important morphologic constructs of the gland, often leading to low sensitivity for the location and grade of PCa [4]. The role of MRI in selection of patients for active surveillance, focal therapy, or nerve-sparing surgery remains controversial.