Re: Topography of lymph node metastases in prostate cancer patients undergoing radical prostatectomy and extended lymphadenectomy: Results of a combined molecular and histopathologic mapping study

摘要

The authors' objective was to evaluate the extent of pelvic lymphadenectomy (PLND) during radical prostatectomy by investigating the topography of lymph node (LN) metasta-ses. Their work was based on the histopathologic and molecular evaluation of LNs dissected from a total of 52 patients, 15 intermediate risk and 37 high risk, who underwent extended PLND up to the bifurcation of the aorta. Histopathologic examination was performed in all LNs, and LNs >3 mm in diameter underwent additional investigation with quantitative reverse transcriptase-polymerase chain reaction.