Re: Prostate cancer screening in the randomized prostate, lung, colorectal, and ovarian cancer screening trial: Mortality results after 13 years of follow-up

摘要

Expert's summary:The prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial included 76 685 men, ages 55-74 yr, randomized to what the authors termed systematic versus opportunistic screening. At 13 yr of follow-up, there was a small increase in prostate cancer incidence in the systematic screening arm (relative risk: 1.12; 95% confidence interval [CI], 1.07-1.17) but little difference in prostate cancer mortality (relative risk: 1.09; 95% CI, 0.87-1.36). There was no evidence of a difference in effect depending on age, pretrial screening, or comorbidity.