Early postural blood pressure response and cause-specific mortality among middle-aged adults: What is the role of diastolic blood pressure?

摘要

With interest we have read the article by Fedorowski et al. [1], which provides valuable information about cause-specific mortality in middle-aged subjects with orthostatic hypotension. In their study orthostatic hypotension (defined as a decrease in systolic blood pressure >20 mmHg and/or decrease in diastolic blood pressure >10 mmHg within 3 min of standing) was associated with mortality through injuries and neurologic diseases. Our major comment is that the article lacks data on the postural diastolic pressure response, both in describing the whole group with ortho-static hypotension, and the analyses of all cause and cause-specific mortality.