S35. Introduction into the consensus topic

摘要

Aspirin & non-steroidal anti-inflammatory drugs (NSAIDs) have been investigated for their cancer preventive properties for more than four decades. During that time, reports from experimental & clinical research have provided strong evidence of Aspirin's benefits in reducing the risk of colorectal cancer; suggestive evidence indicates it may be beneficial for cancers of the esophagus, prostate, breast, & pancreas in women. Aspirin & NSAIDs may prevent cancer through anti-inflammatory or anti-angiogenic actions, or through some as yet unknown mechanism-of-action. For example, Aspirin acts as an anti-inflammatory agent by inhibiting prostaglandin synthesis by cyclo-oxygenase enzymes, which are produced by the body during inflammation. In addition, NSAIDs