White matter ischaemia and carotid plaque morphology re: association between white matter ischaemia and carotid plaque morphology as defined by high resolution in vivo MRI. Eur J Vasc Endovasc Surg 2009 38: 149-154.

摘要

We read with interest the recent article in The European Journal of Vascular and Endovascular Surgery by Patterson et al1. The main causative factor of WMI is small vessel disease, however, there is some evidence for a link with carotid disease2'3. Although a significant relationship was demonstrated a significant relationship between ipsilateral WMI and complex carotid plaque (defined histologically)2 in 57 patients, an analysis of the contralateral carotid plaque was not possible. Using high resolution MRI to assess carotid plaque morphology of only 40 patients with carotid disease (21 symptomatic), Patterson et al found no relationships between any of the morphological features and the severity of WMI.