Anterior Column Reconstruction Using Titanium Ring Cages in Severe Vertebral Osteomyelitis

摘要

Background and Purpose: The use of instrumentation in spinal infections is still a controversial issue.The aim of the present study was to evaluate the efficiency of titanium cages in the surgical treatment of severe vertebral osteomyelitis (synonym spondylodiscitis) concerning eradication of the infection as well as biomechanical aspects.Materials and Methods:The peri-and postoperative data of 43 consecutive patients with vertebral osteomyelitis who underwent single-stage posterior stabilization, anterior debridement including decompression,and anterior column reconstruction using modular titanium ring cages filled with autologous bone were analyzed retrospectively. In 29 cases, a clinical and radiological follow-up of on average 25 years (median 2.2 years) was available.To assess the course of spinal alignment, a detailed radiometric analysis was performed.Results: The time of symptoms prior to surgery averaged 4.6 months. Preoperatively, 37% of the patients showed neurologic compromise with partial or complete recovery in 88% after surgery In 25 patients (58%), a germ was isolated with Staphylococcus aureus being the most frequent pathogen (44%). Except for one patient with anterior revision and exchange of the cage for persistent infection, primary eradication of the infection was accomplished in all patients. At follow-up, all infections were eradicated, and all cages appeared radiographically fused,The present loss of correction in the sagittal plane amounted 1.5 deg at the affected segment(s) reconstructed by cage interposition and 4,4 deg at posterior fusion levels,Conclusion: Single-stage posterior instrumentation and fusion combined with anterior debridement and anterior column reconstruction using modulartita-nium ring cages represent a safe and efficient strategy in cases of severe vertebral osteomyelitis necessitating surgery. The use of titanium cages guarantees long-term maintenance of correction without increased risk of persistent or recurrent infection.