Clinical treatment outcomes of periodontal therapy in HIV-seropositive patients undergoing highly active antiretroviral therapy.

摘要

INTRODUCTION: Since the worldwide HIV/AIDS epidemic started, various oral manifestations have been described. However, scientific assessment of therapeutic outcomes of chronic periodontitis in HIV-seropositive patients, in particular undergoing highly active antiretroviral therapy (HAART), has not been addressed. MATERIALS AND METHODS: 22 patients divided into a HIV-1-seropositve test group and seronegative control group were studied for 12+ months after receiving periodontal therapy by conservative scaling and root planning and maintenance care. RESULTS AND CONCLUSIONS: Periodontal inflammatory parameters improved significantly under the immune reconstituting influence of HAART without major statistical differences in both examination groups. According to this standardized interventional concept, HIV-1-seropositive patients with chronic periodontal disease can be treated successfully. The treatment outcome in maintaining the periodontal attachment is equally well represented in both clinically controlled groups.