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Gold nanopartiele-coated biomaterial as SERS micro-probes

机译:纳米金包覆的生物材料作为SERS微探针

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摘要

We report for the first time, on the utility of plant-based biomaterial as enhanced-Raman scattering probes. The bio-substrate used in this study are commonly found in plant extracts, and are cost-effective, mechanically robust, flexible and easily transportable. The probe was fabricated by coating the plant extract with gold nanoparticles and characterized. By employing a 'single-touch contact' method, we reveal the ability of these probes to detect routinely used Raman markers such as 2-napthalenethiol and rhodamine B, at nano-molar concentrations, in dry and liquid forms, respectively. Reproducibility of the signals with variation <5%, and the ability to detect biomolecules are demonstrated herein. We envision these bio-probes as potential candidates for enhanced Raman sensing in chemical, environmental, and archaeological applications. By further engineering the shape, morphology, and surface chemistry of these micro-probes, we foresee their utility as miniaturized, natural SERS substrates.
机译:我们首次报告了基于植物的生物材料作为拉曼散射探针的实用性。本研究中使用的生物底物通常存在于植物提取物中,并且具有成本效益,机械坚固,灵活且易于运输。通过用金纳米颗粒包被植物提取物来制备探针并进行表征。通过采用“单点接触”方法,我们揭示了这些探针能够以纳米摩尔浓度分别检测干燥和液体形式的常规使用的拉曼标记,例如2-萘硫醇和若丹明B。本文证明了变异度小于5%的信号的重现性以及检测生物分子的能力。我们设想这些生物探针在化学,环境和考古应用中有望成为增强拉曼传感的潜在候选者。通过进一步设计这些微探针的形状,形态和表面化学,我们可以预见它们作为小型天然SERS底物的用途。

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