Efficacy and tolerability of levetiracetam in children with epilepsy.

摘要

OBJECTIVE: To assess the efficacy and tolerability of levetiracetam (Lev) in children with epilepsy. METHODS: Open-label observational, prospective, single arm, non-interventional study examining patients (/=50%. Observed side effects were somnolence, dysphoria, nervousness, dystrophy, somnipathy, asitia, debilitation, etc. and the incidence rate in the study was 47.5%. Four (3.3%) of 120 patients withdrew because of intolerance of side effects. The estimated one year retention rate of levetiracetam was 73.3%. Poor effect was the most common reason for withdrawal. CONCLUSIONS: In our study, it seemed that levetiracetam was safe and effective for a wide range of epileptic seizures in children with epilepsy.