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Comparison of intracavitary brachytherapy and stereotactic body radiotherapy dose distribution for cervical cancer: In regard to Cengiz etal.

机译:腔内近距离放射疗法和立体定向放射疗法对子宫颈癌剂量分布的比较:关于Cengiz等。

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To the Editor: We have read with interest the comparison by Dr Cengiz et al. (1). In the last decade, technological advancements in tumor imaging, treatment planning, and various forms of high-precision delivery techniques have been dramatic, definitely leading to favorable toxicity profiles (2). Gynecologic brachytherapy has also embraced these new tools for three-dimensional Image-guided adaptive implants. The CT imaging for cervical cancer brachytherapy patients lacks soft tissue definition that has been overcome by MRI (3), and point A-based prescriptions are discouraged (4). The present study used CT-based planning where the current standard is MRI-guided adaptive brachytherapy. The Groupe Europeen de Curietherapie and the European Society for Radiotherapy and Oncology have spearheaded the research in this area with consistent reporting of excellent improved clinical outcomes (5). As such, the volumes advocated, namely intermediate- and high-risk clinical target volumes, cannot be reliably drawr on CT scans without the aid of MRI. Without appropriate target delineation, comparison of plans may be misleading.
机译:致编辑:我们感兴趣地阅读了Cengiz等人的比较。 (1)。在过去的十年中,肿瘤成像,治疗计划和各种形式的高精度递送技术方面的技术进步是惊人的,肯定会带来有利的毒性特征(2)。妇科近距离放射疗法也已经接受了这些新工具,用于三维图像引导的自适应植入物。子宫颈癌近距离放射治疗患者的CT成像缺乏软组织清晰度,而MRI已克服了这种软组织清晰度(3),不建议使用基于A点的处方(4)。本研究使用基于CT的计划,当前的标准是MRI引导的自适应近距离放射治疗。欧洲癌症研究小组和欧洲放射疗法与肿瘤学会共同率先开展了该领域的研究,并不断报告其临床效果得到了显着改善(5)。因此,如果没有MRI的帮助,所建议的体积即中高风险临床目标体积就不能可靠地用于CT扫描。没有适当的目标描述,计划的比较可能会产生误导。

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