Insecticides and pesticides cause severe damage to the developing embryo in the egg of birds and overall fecundity of birds reduces. Developmental toxicity of two different classes of commercial formulations of insecticides treatment was studied on chick embryo. 24 h-LD50. Value of endosulfan and methyl parathion was determined to be 0.58037 mg/egg and 0.406753 mg/egg respectively by probit analysis method. In the next experiment 41 to 45 gm fertilized eggs were kept in 1/5th LD50 dose for 96 hours in an incubator (for endosulfan and methyl parathion it was 0.116 and 0.081 mg/egg respectively). It was found that protein content decreases in both the cases. However, lipid content increases, especially in endosulfan treated eggs. Number of somites was counted in both control and treated eggs. It was found that there is a severe developmental retardation in metacid (malathion) treated eggs including remarkable decrease in the number of somites and deformities in the neural tube.
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