Estimation of serum prolactin levels in patients with primary hypothyroidism

摘要

Introduction: The aim of this study is to see whether routine screening for serum prolactin level in all primary hypothyroid patients is necessary or not. Materials and methods: Primary Hypothyroidism was established initially on the basis of increased TSH and decreased or normal T4 and / or T3 levels in serum. The serum prolactin levels were estimated in all such diagnosed cases (32 cases, 28 females and 4 males) and compared with that of 32 ages and sex matched controls. Results: Differences between mean serum prolactin levels among cases and controls were statistically insignificant (10.19 ± 9.68 pg/L vs 10.73 ±4.76 Hg/L;p > 0.75). No correlation between serum prolactin and TSH levels (p > 0.37, r = - 0.17) among cases was found. Conclusion: Prolactin levels in serum of primary hypothyroid patients of all categories remain within normal limits.