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Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline

机译:用于结肠癌和结肠外结肠癌的自膨胀金属支架:欧洲胃肠内镜协会(ESGE)临床指南

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摘要

This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). This Guideline was also reviewed and endorsed by the Governing Board of the American Society for Gastrointestinal Endoscopy (ASGE). The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system was adopted to define the strength of recommendations and the quality of evidence. Main recommendations The following recommendations should only be applied after a thorough diagnostic evaluation including a contrast-enhanced computed tomography (CT) scan. 1 Prophylactic colonic stent placement is not recommended. Colonic stenting should be reserved for patients with clinical symptoms and imaging evidence of malignant large-bowel obstruction, without signs of perforation (strong recommendation, low quality evidence). 2 Colonic self-expandable metal stent (SEMS) placement as a bridge to elective surgery is not recommended as a standard treatment of symptomatic left-sided malignant colonic obstruction (strong recommendation, high quality evidence). 3 For patients with potentially curable but obstructing left-sided colonic cancer, stent placement may be considered as an alternative to emergency surgery in those who have an increased risk of postoperative mortality, i. e. American Society of Anesthesiologists (ASA) Physical Status ≥ III and/or age > 70 years (weak recommendation, low quality evidence). 4 SEMS placement is recommended as the preferred treatment for palliation of malignant colonic obstruction (strong recommendation, high quality evidence), except in patients treated or considered for treatment with antiangiogenic drugs (e. g. bevacizumab) (strong recommendation, low quality evidence).
机译:本指南是欧洲胃肠内镜协会(ESGE)的官方声明。美国胃肠道内窥镜检查协会(ASGE)的理事会也审查并认可了该指南。建议评估,发展和评估分级(GRADE)系统被用来定义建议的强度和证据的质量。主要建议以下建议仅应在进行全面的诊断评估(包括对比增强的计算机断层扫描(CT)扫描)后应用。 1不建议放置预防性结肠支架。对于有临床症状和影像学证据表明有恶性大肠梗阻且无穿孔迹象的患者,应保留结肠支架术(强烈建议,低质量证据)。 2不建议将结肠自膨式金属支架(SEMS)放置为选择性手术的桥梁,以作为症状性左侧恶性结肠梗阻的标准治疗方法(强烈推荐,高质量的证据)。 3对于可能治愈但阻塞性左侧结肠癌的患者,对于术后死亡率风险较高的患者,可以考虑将支架置入术替代急诊手术。 e。美国麻醉医师学会(ASA)身体状况≥III和/或年龄> 70岁(推荐强度低,证据质量低)。 4建议将SEMS放置作为减轻恶性结肠梗阻的首选治疗方法(强烈推荐,高质量的证据),但对于接受抗血管生成药物(例如贝伐单抗)治疗或考虑进行治疗的患者除外(强烈推荐,低质量的证据)。

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