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首页> 外文期刊>Bulletin of experimental biology and medicine >Lipid composition in rats with nonischemic chronic heart failure.
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Lipid composition in rats with nonischemic chronic heart failure.

机译:非缺血性慢性心力衰竭大鼠的脂质成分。

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The initial stages of nonischemic chronic heart failure in rats (model of oleothorax) were accompanied by the development of dyslipidemia. This state was characterized by an increase in total cholesterol concentration (due to the fraction of low-density lipoproteins) and atherogenicity index. The concentrations of plasma total cholesterol and low-density lipoproteins were shown to decrease in animals with severe course of nonischemic chronic heart failure. These changes were accompanied by a decrease in the atherogenicity index. Intragastric administration of cholesterol had little effect on the lipid composition of blood plasma in rats, irrespective of the severity of heart failure.
机译:大鼠非缺血性慢性心力衰竭的初始阶段(油胸腔模型)伴有血脂异常的发展。这种状态的特征是总胆固醇浓度(由于低密度脂蛋白的分数)和动脉粥样硬化指数增加。在患有非缺血性慢性心力衰竭严重病程的动物中,血浆总胆固醇和低密度脂蛋白的浓度降低。这些变化伴随着动脉粥样硬化指数的降低。无论心力衰竭的严重程度如何,胃内给予胆固醇对大鼠血浆脂质组成的影响均很小。

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