Hemopoietic and Lymphoid Organs in AKR/JY Mice with Thymic Lymphoma.

摘要

Cytological and histological studies of the thymus, bone marrow, peripheral blood, spleen, and lymph nodes in 6-9-month-old AKR/JY mice showed that the risk of thymic lymphoma in these animals increased with age. Generalization of the tumor process was observed in mice aged over 8 months and first involved the spleen, then the lymph nodes, bone marrow, and liver. A case of primary lymphoma in the spleen was detected.