Regulation of NO-producing function of the lungs with salmeterol.

摘要

The state of epithelial nitric oxide synthase, bronchomotor reaction, and concentration of NO metabolites (NO(2)(-) and NO(3)(-)) in bronchoalveolar lavage fluid were studied in healthy rats and rats with experimental bronchial asthma induced by inhalations of long-acting beta(2)-agonist salmeterol. The effects of salmeterol on NO-producing function of the lung in healthy animals and in animals with bronchial asthma were studied.