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首页> 外文期刊>Electrophoresis: The Official Journal of the International Electrophoresis Society >Characterization of the distribution of rotational torque on electrorotation chips with 3D electrodes
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Characterization of the distribution of rotational torque on electrorotation chips with 3D electrodes

机译:具有3D电极的电旋转芯片上旋转扭矩分布的表征

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摘要

This is a study of in-plane and out-of-plane distribution of rotational torque (ROT-T) and effective electric field (EEF) on electrorotation (ER) devices with 3D electrodes using finite element modeling (FEM) and experimental method. The objective of this study is to investigate electrical characteristics of the ER devices with five different electrode geometries and obtain an optimum structure for ER experiments. Further, it provides a comparison between characteristics of the 3D electrodes and traditionally used 2D electrodes. 3D distributions of EEF were studied by the time-variant FEM. FEM results were verified experimentally by studying the rotation of biological cells. The results show that the variations of ROT-T and EEF over the measurement area of the devices are considerably large. This can potentially lead to misinterpretation of recorded data. Therefore, it is essential to specify the boundaries of the measurement area with minimum deviation from the central EEF. For this purpose, FE analyses were utilized to specify the optimal region. Thereby, with confining the measurements to these regions, the dependency of ROT-T on the spatial position of the particles can be eliminated. Comparisons have been made on the sustainability of the EEF and ROT-T distributions for each device, to find an optimum design. Analyses of the devices prove that utilization of the 3D electrodes eliminate irregularities of EEF and ROT-T along the z-axis. The Results show that triangular electrodes provide the highest sustainability for the in-plane ROT-T and EEF distribution, while the oblate elliptical and circular electrodes have the lowest variances along the z-axis.
机译:这是使用有限元建模(FEM)和实验方法对带有3D电极的电旋转(ER)设备上的旋转扭矩(ROT-T)和有效电场(EEF)的平面内和平面外分布的研究。这项研究的目的是研究具有五种不同电极几何形状的ER设备的电特性,并为ER实验获得最佳结构。此外,它提供了3D电极和传统使用的2D电极的特性之间的比较。通过时变有限元法研究了EEF的3D分布。通过研究生物细胞的旋转,通过实验验证了有限元方法的结果。结果表明,ROT-T和EEF在设备测量范围内的变化很大。这可能会导致对记录数据的误解。因此,必须指定与中央EEF的偏差最小的测量区域的边界。为此,利用有限元分析来指定最佳区域。因此,通过将测量范围限制在这些区域,可以消除ROT-T对颗粒空间位置的依赖性。已针对每种设备的EEF和ROT-T分布的可持续性进行了比较,以找到最佳设计。对设备的分析证明,利用3D电极消除了沿z轴的EEF和ROT-T的不规则性。结果表明,三角形电极为面内ROT-T和EEF分布提供了最高的可持续性,而扁圆的椭圆形和圆形电极沿z轴的变化最小。

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