Pharmacokinetics and Safety of Macrocyclic Gadobutrol in Children Aged Younger Than 2 Years Including Term Newborns in Comparison to Older Populations

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Pharmacokinetics and Safety of Macrocyclic Gadobutrol in Children Aged Younger Than 2 Years Including Term Newborns in Comparison to Older Populations

机译：大环加多布特罗在包括足月新生儿在内的2岁以下儿童中的药代动力学和安全性与年龄较大的人群相比

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摘要

Objectives: This clinical study evaluated the pharmacokinetics (PK) and safety data of macrocyclic extracellular contrast agent gadobutrol in pediatric subjects aged younger than 2 years.

机译：目的：该临床研究评估了大环细胞外造影剂加多布特罗在2岁以下儿童中的药代动力学（PK）和安全性数据。

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《Investigative radiology》 |2016年第1期|共8页
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正文语种 eng
中图分类放射医学;
关键词
gadobutrol; magnetic resonance imaging; children; newborns; population pharmacokinetics; macrocyclic;

机译：加多布特罗;磁共振成像;儿童;新生儿;人群药代动力学;大环;

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1. Pharmacokinetics and Safety of Macrocyclic Gadobutrol in Children Aged Younger Than 2 Years Including Term Newborns in Comparison to Older Populations [J] . Investigative radiology . 2016,第1期

机译：大环加多布特罗在包括足月新生儿在内的2岁以下儿童中的药代动力学和安全性与年龄较大的人群相比
2. Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults. [J] . Gupta SK, Kantesaria B, Banfield C, British Journal of Clinical Pharmacology . 2007,第2期

机译：6个月至2岁儿童的地氯雷他定剂量选择：儿童和成人之间人群药代动力学的比较。
3. Desloratadine dose selection in children aged 6?months to 2?years: comparison of population pharmacokinetics between children and adults [J] . Samir K. Gupta, Bhavna Kantesaria, Christopher Banfield, British journal of clinical pharmacology . 2007,第2期

机译：6个月至2岁的儿童中的地氯雷他定剂量选择：儿童与成人之间人群药代动力学的比较
4. LONG-TERM (100-300 YEARS) INTERIM DRY STORAGE FOR SPENT FUEL: PACKAGE AND FACILITIES DEVELOPMENT INCLUDING SAFETY ASPECTS AND DURABILITY ASSESSMENT PROGRAM [C] . J.-P. SILVY, N. MOULIN, F. LAURENT, NATO Advanced Research Workshop on Safety Related Issues of Spent Nuclear Fuel Storage . 2007

机译：长期（100-300岁）废燃料中的临时干燥储存：包装和设施开发，包括安全方面和耐用性评估计划
5. A questionnaire-based analysis of the food safety knowledge of primary food handlers for children eight years old and younger [D] . Hamade, Nariman H. 2015

机译：基于问卷的八岁及以下儿童初级食品从业人员食品安全知识分析
6. Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults [O] . Samir K Gupta, Bhavna Kantesaria, Christopher Banfield, 2007

机译：6个月至2岁儿童的地氯雷他定剂量选择：儿童与成人之间人群药代动力学的比较
7. Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults [O] . Gupta, Samir K, Kantesaria, Bhavna, Banfield, Christopher, 2007

机译：6个月至2岁儿童的地氯雷他定剂量选择：儿童与成人之间人群药代动力学的比较
8. Child Safety Restraint Study: A Study of the Effects of Child Safety Restraint Legislation on the Incidence and Severity of Motor Vehicle Accident Injuries to Children Six Years of Age and Younger (Based on 1980-1982 and 1984-1985 Accidents) [R] . 1986

机译：儿童安全约束研究：儿童安全约束立法对6岁及以下儿童机动车事故伤害发生率和严重程度的影响研究（基于1980-1982和1984-1985事故）

Pharmacokinetics and Safety of Macrocyclic Gadobutrol in Children Aged Younger Than 2 Years Including Term Newborns in Comparison to Older Populations

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