Pain in interstitial cystitis/bladder pain syndrome: do characteristics differ in ulcerative and non-ulcerative subtypes?

摘要

Introduction and hypothesis Key differences between interstitial cystitis/bladder pain syndrome (IC/BPS) subtypes (with and without Hunner's ulcer) have been noted. We hypothesized that pain characteristics in women grouped by IC/BPS subtype would differ.Methods A survey was mailed to 749 women to assess IC/BPS pain and other characteristics. Cystoscopy/ hydrodistention reports were reviewed for presence/absence of Hunner's ulcer. The McGill Pain Questionnaire Short Form (MPQ-SF), Brief Pain Inventory (BPI), and Interstitial Cystitis Symptom and Problem Indices (IC SI-PI) assessed symptoms. Data were analyzed with Pearson's chi-square, Fisher's exact, t tests, and Wilcoxon rank tests.Results Of the 214 women that returned a survey (36 ulcerative and 178 non-ulcerative IC/BPS), similar proportions in each group reported that certain foods, exercise, and/or stress triggered symptoms. Fewer ulcerative patients reported pain with vaginal penetration than non-ulcerative (5/33,15.2 % vs 76/160, 47.5 %; p=0.0006). On the BPI, the ulcerative and non-ulcerative groups reported similar numbers of painful areas (mean 4.1 ±6.1 and 4.1 ±3.8; p=0.33), and lower abdominal/pelvic pain was reported most (13/35, 37 % vs 79/ 172,46 %;p=0.34) followed by lower back pain (12/35,34 % vs 69/172, 40 %; p=0.52).