Comment on Xue et al.: Alendronate treatment improves bone-pedicle screw interface fixation in posterior lateral spine fusion: an experimental study in a porcine model.

摘要

We read the article entitled "Alendronate treatment improves bone-pedicle screw interface fixation in posterior lateral spine fusion: an experimental study in a porcine model" by Qingyun Xue et al. with great interest [1]. The purpose of the research was to investigate whether alendronate treatment improves bone-pedicle screw interface fixation in posterior lateral spine fusion. We would like to thank the authors for their innovative and encouraging paper, but we have some concerns about the safety profile of alendronate.