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Treatment of primary malignant bone tumours of the distal tibia.

机译:胫骨远端原发性恶性骨肿瘤的治疗。

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We treated 15 patients with primary malignant bone tumours of the distal tibia of which 14 were treated by limb salvage surgery. Reconstructions were done by allografts with or without microvascular fibula transfer, by bone transport, by fibula transfer alone or by endoprosthetic replacement. The most successful methods were bone transport and endoprosthetic replacement. However, serious complications with deep infections leading to secondary amputation occurred in four patients and in all reconstruction groups. After a mean follow up of 7 years, no local recurrence occurred, and all patients were alive and free of disease. After radical resection, bone transport in defects less than 15 cm is a viable option. In larger defects in children, allograft with vascularised fibula is an acceptable alternative, but amputation still has a role in this group. In adults, endoprosthetic replacement with proper soft tissue coverage is a viable option in cases with large bony defects.
机译:我们治疗了15例胫骨远端原发性恶性骨肿瘤患者,其中14例通过肢体抢救手术治疗。通过同种异体移植(有或没有微血管腓骨转移),骨运输,单独的腓骨转移或通过人工修复进行重建。最成功的方法是骨运输和人工修复。但是,在四名患者和所有重建组中均发生了严重的并发症,并伴有深部感染,导致继发截肢。平均随访7年后,未发生局部复发,所有患者均活着并且没有疾病。根治性切除后,缺损小于15 cm的骨运输是可行的选择。对于儿童较大的缺损,异体移植血管化腓骨是可以接受的替代方法,但截肢在这一组中仍然起作用。在成年人中,在骨缺损较大的情况下,用适当的软组织覆盖物进行人工修复是一种可行的选择。

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