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Intraocular pressure control after the implantation of a second Ahmed glaucoma valve.

机译:植入第二个艾哈迈德青光眼瓣膜后进行眼内压控制。

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The objective of this study is to evaluate the efficacy and safety of a second Ahmed glaucoma valve (AGV) in eyes with refractory glaucoma that had undergone prior Ahmed device implantation. This multicenter, retrospective study evaluated 58 eyes (58 patients) that underwent a second AGV (model S2-n?=?50, model FP7-n?=?8) due to uncontrolled IOP under maximal medical therapy. Outcome measures included IOP, visual acuity, number of glaucoma medications, and postoperative complications. Success was defined as IOP <21?mmHg (criterion 1) or 30?% reduction of IOP (criterion 2) with or without hypotensive medications. Persistent hypotony (IOP <5?mmHg after 3?months of follow-up), loss of light perception, and reintervention for IOP control were defined as failure. Mean preoperative IOP and mean IOPs at 12 and 30?months were 27.55?±?1.16?mmHg (n?=?58), 14.45?±?0.83?mmHg (n?=?42), and 14.81?±?0.87?mmHg (n?=?16), respectively. The mean numbers of glaucoma medications preoperatively at 12 and 30?months were 3.17?±?0.16 (n?=?58), 1.81?±?0.2 (n?=?42), and 1.83?±?0.35 (n?=?18), respectively. The reductions in mean IOP and number of medications were statistically significant at all time intervals (P?
机译:这项研究的目的是评估第二个艾哈迈德青光眼瓣膜(AGV)在先前接受过艾哈迈德装置植入的难治性青光眼中的疗效和安全性。这项多中心回顾性研究评估了58眼(58例患者),这些眼因最大的药物治疗下IOP不受控制而接受了第二次AGV(S2-n?=?50,FP7-n?=?8)。结果指标包括眼压,视力,青光眼用药数量和术后并发症。成功定义为有或没有降压药物时IOP <21?mmHg(标准1)或IOP降低30%(标准2)。持续性肌张力低下(随访3个月后,IOP <5?mmHg),光知觉丧失和对IOP控制的再次干预被定义为失败。术前平均眼压和12个月和30个月时的平均眼压分别为27.55±1.16mmHg(n = 58),14.45±0.83mmHg(n = 42)和14.81±0.87。 mmHg(n≥16)。术前12和30个月的青光眼药物平均数为3.17±0.16(n = 58),1.81±0.2(n = 42)和1.83±0.35(n == 53)。 18)。在所有时间间隔内,平均眼压和药物数量的减少均具有统计学意义(P <0.001)。根据准则1,Kaplan-Meier生存曲线显示在12个月时成功率为62.9%,在30个月时成功率为56.6%。根据准则2,Kaplan-Meier生存曲线显示,在12个月时成功率为43.9%,在30个月时成功率为32.9%。最常见的早期并发症是高血压期(10.3%),最常见的晚期并发症是角膜浮肿(17.2%)。二次AGV植入可有效降低青光眼不受控制的眼内压,并伴有相对较少的并发症。

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