What's missing for evidence-based fever management? Is fever beneficial or harmful to humans?

摘要

Fever is a common symptom in patients with infection, injury or various inflammatory-related diseases. Since between 29% and 36% of hospitalized patients are estimated to have fever (Bor et al., 1988; McGowan et al., 1987), fever management is an important nursing practice that requires serious study not only because it influences patients' health outcomes but also because providing antipyretic therapy consumes considerable resources and nursing manpower. Physiologically, fever is a complex, coordinated and self-contained response that is induced by a group of pyrogens (Dinarello, 2004).