Detection and Automated Scoring of Dicentric Chromosomes in Nonstimulated Lymphocyte Prematurely Condensed Chromosomes After Telomere and Centromere Staining

Mkacher Radhia; El Maalouf Elie; Terzoudi Georgia; Ricoul Michelle; Heidingsfelder Leonhard; Karachristou Ionna; Laplagne Eric; Hempel William M.; Colicchio Bruno; Dieterlen Alain; Pantelias Gabriel; Sabatier Laure

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Detection and Automated Scoring of Dicentric Chromosomes in Nonstimulated Lymphocyte Prematurely Condensed Chromosomes After Telomere and Centromere Staining

机译：端粒和着丝粒染色后非刺激性淋巴细胞过早浓缩染色体中双着丝粒染色体的检测和自动评分

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Purpose: To combine telomere and centromere (TC) staining of premature chromosome condensation (PCC) fusions to identify dicentrics, centric rings, and acentric chromosomes, making possible the realization of a dose-response curve and automation of the process.

机译：目的：结合早染色体浓缩（PCC）融合的端粒和着丝粒（TC）染色来鉴定双着丝粒，中心环和无心染色体，从而实现剂量反应曲线和过程自动化。

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《International Journal of Radiation Oncology, Biology, Physics》 |2015年第3期|共10页
作者
Mkacher Radhia; El Maalouf Elie; Terzoudi Georgia; Ricoul Michelle; Heidingsfelder Leonhard; Karachristou Ionna; Laplagne Eric; Hempel William M.; Colicchio Bruno; Dieterlen Alain; Pantelias Gabriel; Sabatier Laure;
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正文语种 eng
中图分类放射医学;
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1. Detection and Automated Scoring of Dicentric Chromosomes in Nonstimulated Lymphocyte Prematurely Condensed Chromosomes After Telomere and Centromere Staining [J] . Mkacher Radhia, El Maalouf Elie, Terzoudi Georgia, International Journal of Radiation Oncology, Biology, Physics . 2015,第3期

机译：端粒和着丝粒染色后非刺激性淋巴细胞过早浓缩染色体中双着丝粒染色体的检测和自动评分
2. Triage biodosimetry using centromeric/telomeric PNA probes and Giemsa staining to score dicentrics or excess fragments in non-stimulated lymphocyte prematurely condensed chromosomes [J] . Karachristou Ioanna, Karakosta Maria, Pantelias Antonio, Mutation Research - Genetic Toxicology and Environmental Mutagenesis . 2015,第Null期

机译：使用着丝粒/端粒PNA探针和Giemsa染色进行分流生物剂量测定，对未受刺激的淋巴细胞过早浓缩的染色体中的双着丝粒或过量片段进行评分
3. Simple biodosimetry method for use in cases of high-dose radiation exposure that scores the chromosome number of Giemsa-stained drug-induced prematurely condensed chromosomes (PCC). [J] . Gotoh E, Tanno Y, Takakura K International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2005,第1期

机译：一种简单的生物剂量测定方法，用于对大剂量放射线进行照射的情况，该方法可对Giemsa染色的药物诱导的早凝染色体（PCC）的染色体数进行评分。
4. Automated identification of centromere position and centromere index(CI) of human chromosome images [C] . Loganathan E., Anuja M.R, Madian Nirmala 2012 International Conference on Machine Vision and Image Processing. . 2012

机译：自动识别人类染色体图像的着丝粒位置和着丝粒指数（CI）
5. Centromere structure and behavior: Insight from engineered dicentric chromosomes. [D] . Higgins, Anne Whalen. 2000

机译：着丝粒的结构和行为：工程双心染色体的见解。
6. Stabilization of dicentric chromosomes in Saccharomyces cerevisiae by telomere addition to broken ends or by centromere deletion. [O] . D Jäger, P Philippsen 1989

机译：通过端粒添加到末端或通过着丝粒删除来稳定酿酒酵母中的双着丝粒染色体。
7. Detection and Automated Scoring of Dicentric Chromosomes in Nonstimulated Lymphocyte Prematurely Condensed Chromosomes After Telomere and Centromere Staining [O] . M’kachera, Radhia, Maalouf, Elie, Terzoudi, Georgia, 2015

机译：端粒和着丝粒染色后，非刺激性淋巴细胞过早浓缩的染色体中双着丝粒的检测和自动评分
8. Persistence of Lymphocytes with Dicentric Chromosomes Following Whole-Body XIrradiation of Mice [R] . Kilgerman, A. D., Halperin, E. C., Erexson, G. L., 1990

机译：全身照射小鼠后具有双中心染色体的淋巴细胞的持久性

Detection and Automated Scoring of Dicentric Chromosomes in Nonstimulated Lymphocyte Prematurely Condensed Chromosomes After Telomere and Centromere Staining

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