COSTELLO SYNDROME COMMUNITY MOURNS NEW ZEALAND PEDIATRICIAN Jack Costello remembered for his support of families affected by the condition

摘要

When New Zealand pediatrician Jack Costello, MD, died in December 2010, he left a disorder bearing his name and hundreds of families and researchers grateful for his astute clinical observations and the research and treatment advances they made possible. Dr. Costello first identified a relationship between 2 children's intellectual disabilities, poor growth, similar facial appearance, and wart-like growths called nasal papillomata in 1971 [Costello, 1971]. In 1977, Dr. Costello published more detailed observations in the New Zealand Medical Journal [Costello, 1977]. Nearly 20 years later, when the disorder was well known as Costello syndrome (CS), he wrote about those 2 patients in a follow-up that added a list of adult features including high blood pressure, breast fibroadenoma, and skeletal complications including scoliosis and tight Achilles tendons [Costello, 1996].