Identification of high-risk plaques associated with peri-procedural myocardial injury following elective percutaneous coronary intervention: Assessment by high-sensitivity troponin-T measurements and optical coherence tomography

摘要

A worse prognosis of peri-procedural myocardial injury (PMI) following percutaneous coronary intervention (PCI) has been reported in patients displaying an isolated elevation of cardiac troponin-T (TnT) or troponin-1 [1,2]. Highly sensitive assay for TnT (hs-TnT) is newly developed, permitting measurement of TnT than those measurable limit with conventional assays [3,4]. Thus, procedural changes in TnT values following PCI using the hs-TnT assay may identify more minute myocardial injury. Optical coherence tomography (OCT) with high-resolution images (approximately equal to 15um) allows detailed information such as fibrous cap thickness, and lipid distribution of the atherosclerotic plaque in vivo [5]. Therefore, this study has focused on precise assessments for PMI and lesion characteristics using both the hs-TnT measurements and OCT imaging.