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Insufficient use of mineralocorticoid receptor antagonists in patients that underwent renal sympathetic denervation for resistant hypertension

机译:肾交感神经去神经治疗顽固性高血压患者中盐皮质激素受体拮抗剂的使用不足

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摘要

The prevalence of hypertension appears to be around 30-54% of the general population but only one third of the patients are under control. Hypertension is defined as resistant to treatment when a therapeutic strategy that includes appropiate lifestyle measures plus a diuretic and two other antihypertensive drugs belonging to different classes at adequate doses. It is assosiated with high risk of cardiovascular morbidity and mortality. Denervation of renal sympathetic nerves with radiofrequency ablation catheter is a new non-drug, therapeutic approach in the treatment of resistant hypertension (RH) [1 ]. Recent guidelines for the management of arterial hypertension addressed renal sympathetic denervation (RSD) as a Class lib recommendation for the patients with truly RH (clinic BP > 160/ 110 mm Hg confirmed by ambulatory BP monitoring) [1,2
机译:高血压的患病率大约占总人口的30-54%,但只有三分之一的患者处于受控状态。当一种治疗策略包括适当的生活方式措施以及适当剂量的利尿药和两种其他属于不同类别的降压药时,高血压被定义为对治疗有抵抗力。它与心血管疾病发病率和死亡率的高风险有关。射频消融导管去神经交感神经是一种新的非药物治疗方法,用于治疗抵抗性高血压(RH)[1]。最新的动脉高血压管理指南将肾交感神经失调(RSD)作为真正的RH(通过动态BP监测证实的BP> 160/110 mm Hg的患者)的类lib建议。

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