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Reflective meniscometry: a non-invasive method to measure tear meniscus curvature.

机译:反射型粘度计:一种测量泪液弯月面曲率的非侵入性方法。

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摘要

AIMS: To devise a method to measure tear meniscus curvature by a non-invasive specular technique. METHODS: A photographic system was devised. The system consisted of a camera and an illuminated target with a series of black and white stripes oriented parallel to the axis of the lower tear meniscus. The target was mounted on a flash gun close to the objective of a Brown macrocamera and calibrated using a graduated series of glass capillaries of known diameter, ground down to expose the inner wall. It was then applied to normal human eyes (n = 45) to measure the tear meniscus curvature. A video system was also assessed which provided qualitative online information about the tear meniscus. RESULTS: Using the photographic system, measured values for capillary radii were in excellent agreement with theoretical calculations (r2 = 0.996, p < 0.0001). The radii of curvature of lower tear menisci in normal human subjects (mean 0.365 (SD 0.153) mm, range 0.128-0.736; n = 45) were similar to those reported in the literature. Both systems demonstrated variations in meniscus shape. The video system provided stable images of human menisci over prolonged periods of time and promises to be useful for the analysis of dynamic changes in meniscus volume. CONCLUSIONS: Reflective meniscometry is a non-invasive technique providing quantitative information about tear meniscus shape and volume and of potential value in the study of ocular surface disease.
机译:目的:设计一种通过无创镜面技术测量泪液弯月面弯曲度的方法。方法:设计了摄影系统。该系统由一台照相机和一个照明目标组成,该照明目标具有一系列平行于下泪液弯液面轴的黑白条纹。将靶子安装在接近布朗微距相机物镜的闪光灯上,并使用一系列直径已知的带刻度的玻璃毛细管进行校准,将其研磨以暴露内壁。然后将其应用于正常人眼(n = 45)以测量泪液弯月面弯曲度。还评估了一个视频系统,该系统提供了有关泪液半月板的定性在线信息。结果:使用照相系统,毛细管半径的测量值与理论计算值非常吻合(r2 = 0.996,p <0.0001)。正常人下泪液半月板的曲率半径(平均0.365(SD 0.153)mm,范围0.128-0.736; n = 45)与文献报道的相似。两种系统都显示出弯月面形状的变化。该视频系统可长时间提供人类半月板的稳定图像,并有望用于分析半月板量的动态变化。结论:反射型粘度计是一种非侵入性技术,可提供有关泪液半月板形状和体积以及眼表疾病研究潜在价值的定量信息。

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