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A lifetime of healthy skin: implications for women.

机译:一生健康的皮肤:对女性的影响。

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During her lifetime, a woman faces the possibility of seeking dermatological assistance for a myriad of conditions, including acne, rosacea, striae, photodamage, and skin cancers. It is important for clinicians and patients to be aware of the symptoms of these conditions as well as the most beneficial approaches for prevention, diagnosis, treatment, and management. The life expectancy of women has increased and predictions for the year 2050 estimate the average age at 81 years. This will place women at greater risk for dermatological problems, especially photodamage and skin cancer. In addition, various ethnic groups may manifest these conditions differently. Although acne is most prevalent among teenaged males, most can expect clearing by age 25. Females may continue to experience acne into the adult years, sometimes beyond the age of 40. Although it is not a life-threatening disease, acne may have psychosocial and quality-of-life consequences. Treatments for acne can be topical or systemic, and include retinoids, antibiotics, benzoyl peroxide, azelaic acid, and hormonal therapy. Rosacea is more common in women (especially during menopause) than in men. It is a chronic condition that can cause complications, including telangiectasia, conjunctivitis, and blepharitis. Although there is no cure, rosacea can be managed and controlled with medication. Topical antibiotics, such as metronidazole, and systemic antibiotics, such as tetracycline, clarithromycin, and doxycycline, are used to manage rosacea. Striae, or stretch marks, occur most frequently in pregnant women, adolescents experiencing growth spurts, weight lifters, and the obese. Although not a health threat, they can be psychologically distressing. There are not many treatment options for striae, but topical tretinoin and the pulsed dye laser offer promising results. Intrinsic, or normal, aging of the skin results from the process of chronological aging. Photodamage is skin damage caused by chronic exposure to ultraviolet (UV) light. It is the leading cause of extrinsic aging, or alterations of the skin due to environmental exposure. Estimates indicate that almost half of a person's UV exposure occurs by age 18. Photoaging causes numerous histologic, physiologic, and clinical changes; it also increases the risk for skin cancer. Photodamage can be prevented through the use of sun screens, protective clothing, and avoidance of the sun during peak intensity time. The only product approved by the FDA for the treatment of photodamage (fine wrinkles, mottled hyperpigmentation, and skin roughness), topical tretinoin emollient cream, may help prevent additional photoaging when it is used to treat existing photoaging. Other management options for photodamaged skin include alpha-hydroxy acids, antioxidants, antiandrogens, moisturizers, and exfoliants. In patients with excessive manifestations of photodamage, surgical management may be needed, including dermabrasion, chemical peels, soft tissue augmentation, laser resurfacing, botulism toxin, and Gortex threads. Clinicians must educate their patients about the most appropriate skin care regimen as well as approaches for preventing and treating common afflictions. In this way, women will have the best opportunity for having and maintaining healthy skin.
机译:一生中,一名妇女面临着寻求多种病症(包括痤疮,酒渣鼻,条纹,光损伤和皮肤癌)的皮肤病学帮助的可能性。对于临床医生和患者,重要的是要意识到这些疾病的症状以及最有效的预防,诊断,治疗和管理方法。妇女的预期寿命增加了,对2050年的预测估计平均年龄为81岁。这将使妇女更有可能患皮肤病,尤其是光损伤和皮肤癌。此外,各个种族可能会以不同的方式表现这些状况。尽管痤疮在青少年男性中最为普遍,但大多数人都可以期望到25岁时会清除痤疮。女性在成年后可能会继续经历痤疮,有时甚至超过40岁。尽管痤疮不是致命性疾病,但可能与社会心理和社会心理有关。生活质量的后果。痤疮的治疗可以是局部治疗或全身治疗,包括类维生素A,抗生素,过氧化苯甲酰,壬二酸和激素疗法。酒渣鼻在女性(尤其是在更年期)中比男性更常见。它是一种慢性疾病,可能引起并发症,包括毛细血管扩张,结膜炎和睑缘炎。尽管无法治愈,但酒渣鼻可以通过药物治疗和控制。局部抗生素(例如甲硝唑)和全身性抗生素(例如四环素,克拉霉素和强力霉素)可用于治疗酒渣鼻。条纹,妊娠纹最常见于孕妇,出现生长突增的青少年,举重运动员和肥胖者。尽管这不是对健康的威胁,但它们在心理上可能令人痛苦。纹的治疗方法不多,但是局部维甲酸和脉冲染料激光可提供有希望的结果。皮肤固有的或正常的老化是由按时间顺序的老化过程引起的。光损伤是由于长期暴露于紫外线(UV)引起的皮肤损害。它是外在衰老或因暴露于环境而引起皮肤改变的主要原因。估计表明,一个人的紫外线暴露几乎有一半发生在18岁。光老化会引起许多组织学,生理学和临床变化;它还增加了患皮肤癌的风险。可以通过使用防晒霜,防护服以及在峰值强度时间内避免日晒来防止光损坏。唯一的经FDA批准用于治疗光损伤(细皱纹,斑驳的色素沉着和皮肤粗糙)的产品,维甲酸润肤乳膏,在用于治疗现有的光老化时,可能有助于防止额外的光老化。光损伤皮肤的其他管理方法包括α-羟基酸,抗氧化剂,抗雄激素,保湿剂和去角质剂。在光损伤表现过多的患者中,可能需要进行手术管理,包括皮肤磨皮,化学剥皮,软组织增大,激光换肤,肉毒杆菌毒素和Gortex线。临床医生必须教育他们的患者最合适的皮肤护理方案以及预防和治疗常见病的方法。这样,妇女将拥有拥有并保持健康皮肤的最佳机会。

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