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Added effect of heat wave on mortality in Seoul, Korea

机译:热浪对韩国首尔死亡率的影响

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A heat wave could increase mortality owing to high temperature. However, little is known about the added (duration) effect of heat wave from the prolonged period of high temperature on mortality and different effect sizes depending on the definition of heat waves and models. A distributed lag non-linear model with a quasi-Poisson distribution was used to evaluate the added effect of heat wave on mortality after adjusting for long-term and intra-seasonal trends and apparent temperature. We evaluated the cumulative relative risk of the added wave effect on mortality on lag days 0-30. The models were constructed using nine definitions of heat wave and two relationships (cubic spline and linear threshold model) between temperature and mortality to leave out the high temperature effect. Further, we performed sensitivity analysis to evaluate the changes in the effect of heat wave on mortality according to the different degrees of freedom for time trend and cubic spline of temperature. We found that heat wave had the added effect from the prolonged period of high temperature on mortality and it was considerable in the aspect of cumulative risk because of the lagged influence. When heat wave was defined with a threshold of 98th percentile temperature and a parts per thousand yen2, 3, and 4 consecutive days, mortality increased by 14.8 % (7.5-22.6, 95 % confidence interval (CI)), 18.1 % (10.8-26.0, 95 % CI), 18.1 % (10.7-25.9, 95 % CI), respectively, in cubic spline model. When it came to the definitions of 90th and 95th percentile, the risk increase in mortality declined to 3.7-5.8 % and 8.6-11.3 %, respectively. This effect was robust to the flexibility of the model for temperature and time trend, while the definitions of a heat wave were critical in estimating its relationship with mortality. This finding could help deepen our understanding and quantifying of the relationship between heat wave and mortality and select an appropriate definition of heat wave and temperature model in the future studies.
机译:热浪可能会由于高温而增加死亡率。但是,对于高温延长的时间对死亡率产生的附加(持续时间)影响以及根据热浪和模型的定义而产生的不同影响大小的了解很少。在调整了长期和季节内趋势以及表观温度之后,使用具有准泊松分布的分布滞后非线性模型来评估热波对死亡率的附加影响。我们评估了滞后0-30天增加的波浪效应对死亡率的累积相对风险。使用九个热波定义和温度与死亡率之间的两个关系(三次样条和线性阈值模型)构建模型,以忽略高温影响。此外,我们根据时间趋势和温度的三次样条的不同自由度进行了敏感性分析,以评估热波对死亡率的影响。我们发现,高温持续时间较长,热浪对死亡率有附加影响,并且由于滞后影响,在累积风险方面具有相当大的意义。如果将热浪定义为温度阈值第98个百分率,并且连续2天,3和4天每千日元,定义为死亡率,则死亡率分别增加14.8%(7.5-22.6、95%置信区间(CI)),18.1%(10.8-在三次样条模型中,分别为26.0、95%CI),18.1%(10.7-25.9、95%CI)。关于第90个百分位数和第95个百分位数的定义,死亡率的风险增加分别降至3.7-5.8%和8.6-11.3%。这种效应对于温度和时间趋势模型的灵活性具有鲁棒性,而热浪的定义对于估计其与死亡率之间的关系至关重要。这一发现可能有助于加深我们对热浪与死亡率之间关系的理解和量化,并为将来的研究选择合适的热浪与温度模型定义。

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