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Emergency department management of exacerbation of chronic obstructive pulmonary disease: audit of compliance with evidence-based guidelines.

机译:急诊科对慢性阻塞性肺疾病加重的管理:审核循证指南的依从性。

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摘要

BACKGROUND: Emergency departments (ED) play a key role in management of exacerbation of chronic obstructive airways disease (COPD). Current guidelines for management of exacerbation of COPD showed highest levels of evidence (Level A and B) were related to use of medications and non-invasive positive pressure ventilation (NIPPV). Aims: The aim of this study was to examine compliance with high level evidence for management of exacerbation of COPD during the first 4 h of ED care. METHODS: A retrospective medical record audit was conducted at four public and one private ED in Melbourne, Australia. Participants were adult patients with COPD presenting to the ED with a primary complaint of shortness of breath from July 2006 to July 2007. Outcome measures were compliance with evidence-based recommendations regarding use of bronchodilators, methylxanthines, steroids and NIPPV. RESULTS: Of 273 patients in this study, 72.4% received short-acting beta-agonist bronchodilators, 37.8% received an inhaled short-acting anticholinergic medication and 56.6% received systemic steroid therapy. NIPPV was used in 21 patients, 15 of whom had documentation of acidosis and/or hypercapnia). CONCLUSIONS: There was variation in the use of high level evidence for the ED management of exacerbation of COPD. The highest rate of compliance was non-use of methylxanthines and the greatest deficit was poor compliance with evidence related to NIPPV. There was also scope for improvement in the use of bronchodilators and systemic steroids.
机译:背景:急诊科(ED)在慢性阻塞性气道疾病(COPD)恶化的管理中起着关键作用。当前的COPD急性加重治疗指南显示,最高水平的证据(A和B级)与药物的使用和无创正压通气(NIPPV)有关。目的:本研究的目的是检查在ED护理的前4小时内对高水平证据管理COPD恶化的依从性。方法:回顾性病历审核在澳大利亚墨尔本的四个公共和一个私人急诊室进行。参加者为2006年7月至2007年7月向ED急诊的主要COPD成年患者。结果措施符合关于使用支气管扩张药,甲基黄嘌呤,类固醇和NIPPV的循证医学建议。结果:在该研究的273例患者中,有72.4%的患者接受了短效β受体激动剂支气管扩张剂,37.8%的患者接受了吸入的短效抗胆碱能药物,而56.6%的患者接受了全身性激素治疗。 NIPPV用于21位患者,其中15位有酸中毒和/或高碳酸血症的文献。结论:ED治疗COPD急性加重的高级证据使用存在差异。符合率最高的是不使用甲基黄嘌呤,最大的缺陷是对NIPPV相关证据的依从性较差。在使用支气管扩张药和全身性类固醇方面也有改进的余地。

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