Sulfasalazine-induced nephrotic syndrome in a patient with ulcerative colitis.

摘要

Sulfasalazine and 5-aminosalicy-late (5-ASA) have been used for the treatment of inflammatory bowel diseases (IBD) for decades. Nephrotic syndrome related to aminosalicylate use occurs extremely rarely, and there are only a few case reports, which reveal the causative role of sulfasalazine in the development of nephrotic syndrome. We report a case of nephrotic syndrome induced by sulfasalazine, which improved rapidly after the administration of low-dose corticoste-roid therapy and stopping sulfasalazine.