Induction of Labour with Oral Misoprostol vs. IV Oxytocin in Tertiary Care Center

摘要

Aim of Study: 1. To access the efficacy and safety of oral misoprostol in induction of labour. 2. To determine the induction delivery interval. 3. The neonatal outcome. Material and Method The present study was carried out in labour room of dept. of Obstetrics and Gynaecology of NMCH Patna, Bihar. From March 2009 to December 2009. The study was carried out on 100 primigravida patients, age group 20 - 30 years with bishops score > 5, cervical dilatation less than 3 cm, having no contra indication for vaginal delivery and misoprostol use. 50 patients were randomly assigned to receive 25 meg misoprostol orally, 4 hourly maximum up to 6 doses. Another 50 patients with identical clinical criteria were given IV Oxytocin (2 units of Oxytocin in 540 ml of RL). Drip started at 10 drops per minute. Rate increased at half hourly interval by 10 drops to a max. Of 50 drops per minute (i.e 10mu/min), if labour failed to establish the dose was further increased by two units to a max. of 1.6 mu/min. In cases of IUD higher doses up to 8 unit were used". Progress of labour was monitored on the partograph.