SIMPLE TECHNIQUE FOR PREPARING MUCOADHESIVE FILMS

摘要

Polymeric mucoadhesive films are considered highly effective alternative to various other mucoadhesive drug delivery devices like tablets, gels or patches. The moulds or petri dishes generally employed in formulating such mucoadhesive films invariably leads to variation in heterogeneity of film thickness and eventually drug content in the film portion of desired dimensions. This limits the choice of mucoadhesive films prepared using these methods. The current investigation, therefore, reports the design of a quite simple, effective and economical technique for formulation of thin mucoadhesive films and validation of the robustness of the process by monitoring the film thickness, drug content, mucoadhesion and drug release characteristics.