XXXVI Annual Conference of the Indian Pharmacological Society

摘要

Objective: To evaluate the beneficial effects of standardized extracts of Zingiber officinale on elevated glycemic levels in experimentally induced hyperlipidemia and its correlation with 5-HT actions of Zingiber officinale.Methods: Wistar rats of either sex were divided into four groups, Group I served as control, Group II were hyperlipidemic rats which was induced by administering 10% fructose in drinking water, Group III were hyperlipidemic rats treated with methanolic extract of dried rhizomes of Zingiber officinale (250 mg/kg, b.w.), Group IV were hyperlipidemic rats treated with ethyl acetate extract of dried rhizomes of Zingiber officinale (250 mg/kg, b.w.) The drugs were administered orally for 3 weeks, at the end of which blood samples were analyzed for serum glucose, insulin, cholesterol, triglycerides, HDL-cholesterol, LDL and VLDL.