Synthesis of CL-20:By oxidative debenzylation with cerium (IV)ammonium nitrate (CAN)

摘要

Hexanitrohexaazaisowurtzitane (HNIW or CL-20),one of the most powerful high explosives of today,is a polycyclic nitramine cage compound.The synthesis of CL-20 is described from 2,6,8,12-tetraacetyl-4,10-dibenzyl hexaazaisowurtzitane (TADBIW)using debenzylation followed by nitration.TADBIW on reaction with cerium (IV)ammonium nitrate (CAN)gives the debenzylated product,which on nitration with HNO3/H2SO4 provides CL-20.Alternatively,the debenzylated product on acetylation yields 2,4,6,8,10,12-hexaacetyl-2,4,6,8,10,12-hexaazaisowurtzitane (HAIW),which on nitration produces CL-20.