Determining ring-F configuration in spirostane-type steroidal sapogenins by ~1H NMR

摘要

A comparison of ~1H NMR chemical shifts for 25R and 255 spirostane-type steroidal sapogenins and saponins suggest that orientation of 27-Me group has quite a different influence on chemical shifts of the methylene protons occupying P-and Y-positions,thus providing valuable information about the establishment 25R-and 25S-stereochemistry in these compounds.