An efficient method for chemoselective nitration of phenols under mild and heterogeneous conditions

摘要

Nitrophenols can bve obtained via nitrosation-oxidation of phenols with Mg(HSO_4)_2 or NaHSO_4.H_2O, NaNO_2 and wet SiO_2 at room temperature in moderate to high yields. In situ generation of HNO_2 and radical cation mechanism via nitrous acid catalyzed (NAC) pathway appear to be applicable to phenol nitration using these reagents.