Webster dictionary defines, "hybrid is a union or offspring of two distinct species either animal or plant". Some may argue that surgeons and interventional cardiologists are definitely two different species (John P. Cheatham).Perventricular device closure is performed by both surgeon and cardiologist in hybrid suit or operating room combining catheterization and surgical techniques have been described elsewhere.1 This hybrid procedure is useful in a subset of infants, who are otherwise at high risk for surgery or interventional closure. Amin et al first reported successful perventricular device closure in an infant with post operative residual mVSD.2 The indications and guidelines for hybrid perventricular device closure have not been clearly described in literature. However, most of the published data suggests that small babies lesser than 5 kg, children with muscular ventricular septal defects (mVSDs) and other associated cardiac defects--requiring simultaneous repair, who are otherwise at high risk for surgical closure are probably ideal for perventricular device. There is no absolute contraindication to this technique. The present series in this issue by Thakkar et al is probably one of the largest single centre series of perventricular device closure in young children. The authors are congratulated for the nice piece of work in this difficult subset of population. Their study elaborates the technique, complications and outcome of the procedure.
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