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Recommendations of the Second Indo-US Health Summit on Prevention and Control of Cardiovascular Disease among Asian Indians

机译:第二届印美健康峰会关于亚洲印第安人预防和控制心血管疾病的建议

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摘要

Asian Indians, those living in India and also the Diasporas, have one of t he highest rates of coronary artery disease (CAD) in the world. Amongurban Indians the prevalenceof CAD is as high as 10-12%. The CAD among Indians is usually more advanced at the time of presentation compared to whites or other Asians. The overall social and economic impact of the disease is much greater because the CAD in Asian Indians affects a younger and working population. While the mortality and morbidity from CAD has been declining in the western world, it has been climbing among the Indian population. Both established and novel risk factors and a possible genetic predisposition in part due to lipoprotein(a) [Lp(a)] excess and higher prevalence of diabetes appear to significantly contribute to this epidemic. The effects of established as well as novel risk factors are multiplicative not just additive, the total being more than the sum of parts.
机译:亚洲印第安人,居住在印度的人以及流浪者,都是世界上冠心病(CAD)发病率最高的国家之一。在城市印第安人中,CAD的患病率高达10-12%。与白人或其他亚洲人相比,印度人在介绍时的CAD通常更高。该疾病对社会和经济的整体影响要大得多,因为亚洲印第安人的CAD影响了年轻人和劳动人口。尽管在西方世界,CAD的死亡率和发病率一直在下降,但在印度人口中却一直在上升。既定的和新的危险因素以及部分由于脂蛋白(a)[Lp(a)]过量和较高的糖尿病患病率引起的遗传易感性,似乎都对该病造成了重大影响。已确定的风险因素和新的风险因素的影响是乘性的,而不仅仅是累加的,总和大于各部分的总和。

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