Contributions of pulmonary hypertension to HIV-related cardiac dysfunction

摘要

Background/Aim: To evaluate the prevalence of pulmonary hypertension among patients living with HIV/AIDS and to determine its contribution to cardiac dysfunction. Method: A hospital based cross sectional study was carried out over a 6-month period at the Jos University Teaching Hospital. The subjects were 200 confirmed HIV positive patients, >18 years of age who consented to the study. Physical examination, laboratory investigations, 2 dimensional and Doppler echocardiography were conducted on the subjects. Results: The mean age of the patients was 38 +- 9 years, and there were 142 females (71%). Females were younger, mean age 36 +- 8 years versus 41 +- 10 years for males (p-value <0.01). The median CD4 cell count was 312 cellsl, there were no homosexual or intravenous drug user among the subjects.