Synthesis and Phytotoxicity of Structural Analogues of Thaxtomin Natural Products

摘要

Structural analogues of the phytotoxic thaxtomin natural products have been synthesized by building upon a piperazine-dione core and from L-phenylalanine. The compounds were evaluated for their phytotoxic activity against Arabidopsis thaliana seedlings and some of the key features for activity have been identified.