Optimization of Bipolar Pulses of External Defibrillators Based on the Repolarization Hypothesis

摘要

The defibrillation process is simulated using a wide spectrum of spatial models [1]. It is difficult to use most spatial models to simulate and select the optimal bipolar electric defibrillation pulse. In practice, simpler spatial models are used [2, 3].In this work, bipolar pulses of external defibrillators were optimized based on the repolarization hypothesis. The algorithm of the optimization is based on a simple model of defibrillation pulse effect on myocardium cell membrane (Fig. 1) [2, 3]. The defibrillation pulse is applied to resistor R_ (the patient's chest resistance). The signal from resistor R_ is applied to the model of myocardium cell membrane response to an external effector. This model consists of serially connected resistor R~m (cell membrane resistance) and capacitor C~m (cell membrane capacitance).