New Single-Cell, Single-Molecule Method to Identify DNA

摘要

Researchers at NYU and UCLA have developed a method to detect sequence differences in individual DNA molecules by taking nanoscopic pictures of the molecules themselves.Using the approach they call "Direct Molecular Recognition," the UCLA and NYU researchers used nanoparticles to turn the DNA molecules into a form of molecular braille that can be read in the scale of nanometers, or one billionth of a meter, using high-speed Atomic Force Microscopy (AFM).